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Yellow Fever
Flavivirus

A mosquito-borne infection that continues to threaten the lives of people living in tropical areas.

Chapter 1
Yellow Fever Before Its Discovery

A strange febrile disease strikes travelers to the tropics and is brought back to the Americas.

1648
Quarantine in Boston

1732
Death Brings Silence

1747
Philadelphia Avoids an Outbreak

1794
New York Doctor Makes an Important Observation

Chapter 2
The Yellow Fever Virus Is Discovered

Even without advanced technology, scientists discover that yellow fever is caused by a virus.

1899
Yellow Fever Plagues Panama Canal Workers

1900
U.S. Army Researchers Discover the Cause of Yellow Fever

1901
Mosquito Control Efforts Reduce Disease Cases

1931
Steps Taken Toward a Vaccine

Chapter 3
Yellow Fever Vaccine Developed Required for Travel

Countries in the tropical regions of the world use the vaccine to bring yellow fever under control and keep it that way.

1942
Hepatitis Outbreak Prompts Improved Vaccine Safety Measures

1964
Major U.S. Anti-Mosquito Measures Begin

1970
Yellow Fever Mosquito Reappears in South America

January 19, 2016
Angolan Epidemic Stretches Vaccine Supply