Stanley A. Plotkin, MDPhysician, Professor, Researcher, and Vaccine Developer
Chapter 1Before the Isolation and Identification of Rubella Virus
1740Rubella: The "German Measles"
German physician Friedrich Hoffmann was the first to give a clinical description of the disease that would later come to be known as rubella. Until that point, however, so many German physicians were involved in identifying and distinguishing the disease from other known maladies (after Hoffmann’s description, German physicians de Bergen and Orlow confirmed his work) that it would be referred to as “Rötheln,” from the German word Röteln. Thus rubella would also eventually be referred to as “German measles.”
1841Rubella: The Naming of the "Little Red"
1932Stanley Alan Plotkin is born in New York City
1938Rubella: Researchers Demonstrate Transmission of Disease
1941Rubella Implicated in Congenital Defects
1952Stanley Plotkin Earns Bachelor's Degree
1956Stanley Plotkin earns MD from SUNY Downstate Medical Center
1957Dr. Plotkin Joins the Epidemic Intelligence Service
Chapter 2Rubella Isolated, Epidemics of the 1960s, and Dr. Plotkin Begins Work on Vaccines
1962Year in Residency at the Hospital for Sick Children in London and First Encounter With Rubella
1962Rubella Virus Isolated
1964U.S. Rubella Outbreak Infects Millions
A massive rubella outbreak in the United States initially failed to draw serious attention. A Time magazine article encouraged rubella parties, even recommending strategies so that “especially all the little girls get the infection.”
Unfortunately, despite warnings about keeping infected children away from pregnant women, nearly 50,000 women in vulnerable stages of their pregnancies were infected with rubella during the outbreak, leading to thousands of miscarriages and even more children being born with severe damage. At least 8,000 were born deaf, 3,500 deaf and blind; the total number of congenital rubella syndrome cases reached 20,000.
Over the course of the outbreak the country tallied approximately 12.5 million cases of rubella and more than 2,000 deaths. Resulting medical costs reached the billions.
1969Rubella Vaccine Licensed
1971Measles, Mumps, Rubella Vaccine Licensed
Chapter 3Dr. Plotkin After the Rubella Vaccine Success
Dr. Plotkin continued his work in infectious diseases, lecturing, and writing Vaccines, “an indispensable guide to the enhancement of the well-being of our world."